Estrogen receptors (ESR1 and ESR2) play crucial roles in various processes during spermatogenesis.To elucidate individual roles of ESRs in male fertility, we developed in vivo selective ESR agonist administration models.Adult male rats treated with ESR1 and ESR2 agonist for 60 days show spermatogenic defects leading to reduced sperm counts and fert
Multiplexed bioassays, in which multiple analytes of interest are probed in parallel within a single small volume, have greatly accelerated the pace of biological discovery.Bead-based multiplexed bioassays have many technical advantages, including near solution-phase kinetics, small sample volume requirements, many within-assay replicates to reduce
ObjectivesThe vibration-isolation thrust bearing is a new device for the longitudinal vibration control of propulsion shafts.Experimental results show that the dynamic transmission characteristics of the propulsion shaft are quite different from those of theoretical calculation predictions.Analysis shows that there is serious vibration energy leaka